Interaction between oral contraceptives and griseofulvin.

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Difference between drospirenone-containing oral contraceptives and other oral contraceptives related to risk of venous thromboembolism.

We wish to comment on the Dinger and Shapiro commentary article published in the January 2012 issue of this Journal.1 Following the publication of papers regarding the risk of venous thromboembolism (VTE) with combined oral contraceptives (COCs) we would like to share some information regarding comparison between drospirenonecontaining COCs and other COCs in Croatia. This short study was conduc...

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OBJECTIVE Bosentan has been shown in vitro and in vivo to induce the cytochrome P450 enzymes CYP2C9 and CYP3A4. The present study was conducted to investigate the effect of bosentan on the pharmacokinetics of a combined oral contraceptive. SUBJECTS AND METHODS In a randomized, 2-way crossover study, 20 healthy female subjects received Treatments A and B. Treatment A consisted of a single dose...

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Risk of deep vein thrombosis: interaction between oral contraceptives and high factor VIII levels.

BACKGROUND AND OBJECTIVES High levels of factor VIII are a common risk factor for venous thromboembolism (VTE). The aim of this study was to evaluate the possible interaction between the presence of high factor VIII levels and oral contraceptive (OC) use. DESIGN AND METHODS Factor VIII levels were measured by a chromogenic assay in 174 women who suffered from VTE in reproductive age and in 48...

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ژورنال

عنوان ژورنال: BMJ

سال: 1984

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.288.6424.1125-a